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AHPA & CRN Contest NTP Report on Green Tea Extract

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By: Sean Moloughney

Editor, Nutraceuticals World

The American Herbal Products Association (AHPA) and the Council for Responsible Nutrition (CRN) joined forces to express concerns regarding a draft technical report on rodent studies conducted by the National Toxicology Program (NTP) on the toxicology of a specific green tea (Camellia sinensis) extract.

AHPA’s Chief Information Analyst Merle Zimmermann, PhD, presented public oral comments, including those from the written comments submitted by CRN, at a meeting of the Technical Reports Peer Review Panel of the NTP.

Dr. Zimmermann noted that the draft report’s characterization of the tested extract did not include identification of the part of the plant used as a starting material, the solvents or the preparation methods used to make the specific extract. He also testified that since there are many different and unique green tea extracts, NTP should make every effort to clarify that these studies are relevant only to the specific test article. Dr. Zimmermann also offered comments provided by Andrea Wong, PhD, vice president, Scientific & Regulatory Affairs for CRN, in relation to contaminant testing, which was not reported as being conducted for residual solvents, microbiological contaminants or polycyclic aromatic hydrocarbons.

During the meeting, several panel members requested additional information on the characteristics of the extract. Perhaps most importantly, the panel acted formally to downgrade the conclusions presented in the draft report to reflect that there was “no evidence of carcinogenic activity” in either rats or mice, the only species assessed by the NTP.

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